Absorption of drugs from the mouth is better or better

Animal experiments show that BPA can be absorbed through the oral route and directly enter the blood circulation system in the body. This discovery is expected to help people develop drugs that are absorbed through the oral route, so that the drugs are better absorbed.

Researchers at the French National Agricultural Research Institute and other institutions have found in dogs that bisphenol A can directly enter the blood circulation system through the sublingual mucosa covered with blood vessels, and it is comparable to the concentration of bisphenol A in the blood absorbed through the intestine. In contrast, the concentration of bisphenol A absorbed through the oral route in the blood will be nearly a hundred times higher. The researchers believe that replacing bisphenol A with other ingredients should have similar effects.

The announcement said that bisphenol A absorbed through the oral route will not be metabolized in the liver, but directly into the blood. If this absorption method is confirmed in humans, it can help to develop drugs that are absorbed through the oral route, so that the drugs are better absorbed and avoid waste caused by the metabolism of the drugs in the liver.

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